Pharmacokinetics of Edobacomab in Experimental Animals.

Scorpion Venom Pisoning in Experimental Animals

Pharmacokinetics of neothramycin in animals and man.

The pharmacokinetics of neothramycin (NTM) was performed in mice, rabbits and man. Biological half-life of NTM in man after a 20 mg bolus injection produced an alpha phase half-life of 3.63 minutes, a beta phase half-life of 84.5 minutes and a volume of distribution at a steady state of 50.3 liters/body. Its human half-life was longer than those of adriamycin, mitomycin C and neocarzinostatin, ...

Asbestosis in experimental animals.

Previous animal experiments with asbestos dusts have been almost entirely confined to chrysotile asbestos. It was, therefore, decided to investigate the effects of mill dusts from the three types of asbestos that are produced commercially in South Africa, namely chrysotile, amosite, and crocidolite. Chrysotile and amosite samples were relatively pure while in contrast the crocidolite dust was f...

Fasting and Experimental Animals, Detrimental or Positive?

While fasting has been practiced for centuries, its beneficial effects was unknown until recently. This review tries to analyze the current literature of how fasting and intermittent fasting (IF) could affect clinical pathological parameters, learning, mood and brain plasticity. The effects of different ways of fasting on metabolism and stress were also explored. Animal experiments have elucida...

Use of experimental animals.

I shall deal briefly this morning with three topics: (1) the different species and strains of animals to be employed in experimental studies-of bowel cancer with asbestos; (2) combinations of carcinogens; and (3) the difficult and debatable tumors that one sees in experimental animals. I am glad to see that in South Africa baboons are also being used. Frequently Wistar rats are used .or rats of...